The onset of narcolepsy is seasonal, most often surfacing in the spring, following upper respiratory tract infections that had occurred in the preceding months. There is a near-perfect association of type 1 narcolepsy with HLA-DQB1*06:02, leading to the auto-immune hypothesis, which posits a selective, self-destruction of orexin-A producing neurons as the driving force behind the disorder. Type 1 narcolepsy (historically known as narcolepsy with cataplexy) is due to a deficiency of orexin-A, a wakefulness-promoting peptide neurotransmitter. While 19% of patients diagnosed with narcolepsy also get diagnosed with cataplexy, estimates are that roughly 70% of patients with narcolepsy also have cataplexy. Unfortunately, cataplexy is challenging to identify, often going undetected. Subjective descriptions of cataplexy can assist in the identification of narcolepsy, as this feature is all but unique to the disorder. Review the importance of improving care coordination among interprofessional team members to improve outcomes for patients affected by cataplexy.Ĭataplexy, a physical feature of narcolepsy, is characterized by transient episodes of voluntary muscle weakness precipitated by intense emotion.Outline the treatment and management options available for cataplexy.
This activity reviews the role of the interprofessional healthcare team in improving care for patients with narcolepsy, by raising awareness of cataplexy. While one-third of patients present with the classic narcolepsy tetrad (cataplexy, excessive daytime sleepiness, hypnagogic hallucinations, and sleep paralysis), two-thirds of patients with narcolepsy patients are affected by cataplexy. Subjective descriptions of cataplexy can assist in the identification of narcolepsy, as this feature is almost unique to the disorder. Send us feedback.Cataplexy, a physical feature of narcolepsy, is characterized by transient episodes of voluntary muscle weakness precipitated by intense emotion. These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cataplexy.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. 2021 In both cases, more exercise inversely correlated with the degree of sleepiness and frequency of cataplexy episodes experienced. 2021 People with narcolepsy type 2 may experience all the symptoms of narcolepsy except cataplexy-and their symptoms are often less severe, says the National Institute of Neurological Disorders and Stroke (NINDS). 2021 Excessive daytime sleepiness and cataplexy can improve after several weeks of regularly taking sodium oxybate. 2021 Symptoms such as hallucinations, sleep paralysis, and cataplexy may follow, says Manjamalai Sivaraman, MD, FAASM, a sleep medicine specialist and neurologist at the University of Missouri. 2011 According to the Mayo Clinic, the frequency of cataplexy varies tremendously case by case. Elizabeth Preston, Discover Magazine, 30 Aug. 2011 But this view ignores narcolepsy's most ridiculous symptom, called cataplexy.
2014 Not all narcoleptics experience cataplexy, but those who do may lose all strength in their muscles during moments of strong emotion. Elizabeth Preston, Discover Magazine, 29 Aug.
Recent Examples on the Web People with cataplexy, a rare condition tied to narcolepsy, may suddenly lose all their muscle strength and collapse during a fit of laughter.
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